JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles
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JASPAR 2014 : an extensively expanded and updated open-access database of transcription factor binding profiles. / Mathelier, Anthony; Zhao, Xiaobei; Zhang, Allen W.; Parcy, François; Worsley-Hunt, Rebecca; Arenillas, David J.; Buchman, Sorana; Chen, Chih-yu; Chou, Alice; Ienasescu, Hans-Ioan; Lim, Jonathan; Shyr, Casper; Tan, Ge; Zhou, Michelle; Lenhard, Boris; Sandelin, Albin Gustav; Wasserman, Wyeth W.
I: Nucleic Acids Research, Bind 42, 2014, s. D142-D147.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - JASPAR 2014
T2 - an extensively expanded and updated open-access database of transcription factor binding profiles
AU - Mathelier, Anthony
AU - Zhao, Xiaobei
AU - Zhang, Allen W.
AU - Parcy, François
AU - Worsley-Hunt, Rebecca
AU - Arenillas, David J.
AU - Buchman, Sorana
AU - Chen, Chih-yu
AU - Chou, Alice
AU - Ienasescu, Hans-Ioan
AU - Lim, Jonathan
AU - Shyr, Casper
AU - Tan, Ge
AU - Zhou, Michelle
AU - Lenhard, Boris
AU - Sandelin, Albin Gustav
AU - Wasserman, Wyeth W
PY - 2014
Y1 - 2014
N2 - JASPAR (http://jaspar.genereg.net) is the largest open-access database of matrix-based nucleotide profiles describing the binding preference of transcription factors from multiple species. The fifth major release greatly expands the heart of JASPAR-the JASPAR CORE subcollection, which contains curated, non-redundant profiles-with 135 new curated profiles (74 in vertebrates, 8 in Drosophila melanogaster, 10 in Caenorhabditis elegans and 43 in Arabidopsis thaliana; a 30% increase in total) and 43 older updated profiles (36 in vertebrates, 3 in D. melanogaster and 4 in A. thaliana; a 9% update in total). The new and updated profiles are mainly derived from published chromatin immunoprecipitation-seq experimental datasets. In addition, the web interface has been enhanced with advanced capabilities in browsing, searching and subsetting. Finally, the new JASPAR release is accompanied by a new BioPython package, a new R tool package and a new R/Bioconductor data package to facilitate access for both manual and automated methods.
AB - JASPAR (http://jaspar.genereg.net) is the largest open-access database of matrix-based nucleotide profiles describing the binding preference of transcription factors from multiple species. The fifth major release greatly expands the heart of JASPAR-the JASPAR CORE subcollection, which contains curated, non-redundant profiles-with 135 new curated profiles (74 in vertebrates, 8 in Drosophila melanogaster, 10 in Caenorhabditis elegans and 43 in Arabidopsis thaliana; a 30% increase in total) and 43 older updated profiles (36 in vertebrates, 3 in D. melanogaster and 4 in A. thaliana; a 9% update in total). The new and updated profiles are mainly derived from published chromatin immunoprecipitation-seq experimental datasets. In addition, the web interface has been enhanced with advanced capabilities in browsing, searching and subsetting. Finally, the new JASPAR release is accompanied by a new BioPython package, a new R tool package and a new R/Bioconductor data package to facilitate access for both manual and automated methods.
KW - Animals
KW - Arabidopsis
KW - Binding Sites
KW - Caenorhabditis elegans
KW - Databases, Genetic
KW - Drosophila melanogaster
KW - Humans
KW - Internet
KW - Mice
KW - Position-Specific Scoring Matrices
KW - Regulatory Elements, Transcriptional
KW - Transcription Factors
U2 - 10.1093/nar/gkt997
DO - 10.1093/nar/gkt997
M3 - Journal article
C2 - 24194598
VL - 42
SP - D142-D147
JO - Nucleic Acids Research
JF - Nucleic Acids Research
SN - 0305-1048
ER -
ID: 108150762